![]() Online purchases made outside the EU: Purchases made outside the EU may be liable for additional customs tariffs and/or local tax. Please see your cart at the time of purchase. Some goods like digital pianos may incur an additional cost. Irish Orders with a value of over €199 (€200 +) are shipped free of charge unless otherwise stated. This does not affect your statutory rights. Unfortunately X Music Ireland Limited can in no circumstances, therefore, compensate for delayed orders.ĭamages/shortages must be notified within 3 working days of delivery. The delivery charge shown is a standard charge and does not constitute a guarantee of delivery date from the time you have placed an order.Īll delivery times and dates are subject to stock availability in Head Office, the backlog of orders, and Weekend or Bank Holiday exceptions. Unfortunately X MUSIC IRELAND LIMITED cannot guarantee delivery times or dates. The charge for delivery will be shown at the final checkout stage before final submission. A signature at this address will be required. Unless otherwise advised, delivery will be made by a fully-insured courier service, within normal business hours. Responsibility for ownership of the Goods passes to the purchaser once we have delivered them. Intel Core 2 Duo or AMD® Athlon™ X2 processor (Intel Core i3 or AMD Athlon X4 or faster recommended).Intel ® Core™ 2 Duo processor (Intel Core i3 or better recommended).Minimum computer-system requirements for Notion: Seamlessly switch between your Mac/PC and your Windows® Tablet, iPad® or iPhone® (with Notion for iOS available separately)-even perform scores with Notion as your live instrument. Even set music to film with advanced video capabilities.ĭeliver your final professional scores and polished performances with new layout controls MusicXML to transfer between other notation and music apps export WAVs or MP3s with instant SoundCloud sharing.Īnd no other notation software has more options to take your music on the go. Take projects to the next level with deep studio integration including audio/MIDI streaming with any professional DAW via ReWire and unprecedented integration with PreSonus Studio One®. Create music directly on the staff, record or enter notes quickly with a MIDI instrument, or use the integrated virtual Keyboard, Fretboard, or Drum Pad.Ĭreate and perform music with the full realism of samples recorded by the London Symphony Orchestra at Abbey Road Studios Guitars by Neil Zaza, Electric Bass by Victor and Drum Kit by Roy Wooten Olympus Micro Choir and Lakeside Pipe Organ by Soundiron plus enhanced VST support and bundled PreSonus FX. Notion offers tools for scoring to video, offers handwriting recognition (Powered by McScript™), is tightly integrated with PreSonus’ Studio One® DAW, and comes with three Studio One Native Effects plug-ins.īring musical inspirations to life and enhance your creativity with the blazingly fast and intuitive Notion™ 6 music composition and performance environment.Ĭompose traditional notation, tablature, or lead sheets when and how you want-on Mac®, PC, or mobile-even with your own handwriting. Only Notion allows you to create a score on your Mac or Windows computer and transfer it to your iOS device, where you can continue to edit. Offering the finest playback quality of any music notation product, Notion™ features orchestral samples recorded by the London Symphony Orchestra, as well as guitar, bass, and drum samples by Neil Zaza, Victor Wooten, and Roy “Futureman” Wooten. See notation and MIDI data on the same staff.Audio and MIDI ReWire support (host and slave).Import/export files to/from Finale and Sibelius via MusicXML.Compose to picture with the video window (Import video in a variety of formats). ![]() Send audio and MIDI data directly to and from Studio One anywhere on the network.Write parts by hand and watch them convert to digital notation.Create a score on a Mac or Windows computer and continue to edit on iPhone/iPad and vice versa, with Notion for iOS (available separately).Process audio with PreSonus studio One Native Effects Limiter, Compressor, and Pro EQ plug-ins.Perform scores using Notion™ as a live instrument and save your performance.Best playback of any notation product, with orchestral samples recorded by the London Symphony Orchestra and more.Easily compose, playback, and edit music.Download your copy of Notion 6 and start creating straight away.We will send you a download code within 24 hours.
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Perhaps the most powerful part of Unity is the Unity Asset Store, arguably the best asset marketplace in the gaming market. Unity allows you to import and assemble assets, write code to interact with your objects, create or import animations for use with an advanced animation system, and much more.Īs Figure 1 indicates, Unity has done work to ensure cross-platform support, and you can change platforms literally with one click, although to be fair, there’s typically some minimal effort required, such as integrating with each store for in-app purchases. You can do an impressive amount with the free version.) Unity supports all major 3D applications and many audio formats, and even understands the Photoshop. (There’s also a pro version that’s very nice, but it isn’t free. Unity allows you to interact with them via not only code, but also visual components, and export them to every major mobile platform and a whole lot more-for free. I say games and apps because I’ve seen not just games, but training simulators, first-responder applications, and other business-focused applications developed with Unity that need to interact with 2D/3D space. Unity is a 2D/3D engine and framework that gives you a system for designing game or app scenes for 2D, 2.5D and 3D. I’ll show how to create 2D and 3D games and, finally, how to build for the Windows platforms. This is the first article in a four-part series that will cover the basics and architecture of Unity. Then, one day, I decided to experiment with Unity, and I saw it could do some amazing things. I then started on DirectX development but realized that, although it was extremely powerful, it seemed like too much code for what I wanted to do. ![]() I had done some native code graphics programming in the early Windows days, and it wasn’t a fun experience. When it came to making games, though, I was a bit lost as to where to start. Volume 29 Number 8 Unity : Developing Your First Game with Unity and C#Īs a software architect, I’ve written many systems, reverse-engineered native code malware, and generally could figure things out on the code side. Her ability to convey the emotional range required for Coraline's journey is also commendable, making the film a captivating experience for audiences of all ages. Moreover, thanks to Fanning's voice acting, Coraline becomes a more complex and compelling lead character. Two Oregon environmentalists (Jesse Eisenberg, Dakota Fanning) and a former Marine (Peter Sarsgaard) hatch a plan to blow up a hydroelectric dam. ![]() However, things take a sinister turn when she realizes that this magical world and its Other Mother ( Teri Hatcher) has a dark and eerie secret.įanning’s performance is a delightful blend of innocence and courage, perfectly capturing Coraline's curiosity and determination as she faces the Other Mother's sinister intentions. However, unforeseen consequences bring a. They pull in Harmon, a man with a sketchy past, to help them pull off their big plan. ![]() She stumbles upon a hidden door that leads her into an alternate world, seemingly perfect, where everything she desires comes true. Storyline: Night Moves (2013) Josh and Dena, two young environmental activists, are planning a large scale act to force the world to think about what they're doing to the environment. The ghost also turns on the Stairmaster and moves jewelry across the dresser. You can now watch it and every season on Amazon Prime Instant.Based on Neil Gaiman's novella, Coraline is a mesmerizing stop-motion animated dark fantasy film that revolves around Coraline Jones (Fanning), a curious and adventurous young girl who moves to a new home with her neglectful parents. Mama is a 2013 horror film produced by Guillermo del Toro, and based on a. Julianna Margulies just won her second Emmy for “The Good Wife,” the network legal drama that had its best season yet last year. Night Moves is the story of three radical environmentalists coming together to execute the most intense protest of their lives: the explosion of a hydroelect. They paid $2 million an episode so they must be confident that there’s an audience for it. TV binge watch: Looking to catch up on your favorite shows before the new season begins? Netflix now has every episode of these fan-favorite shows: “Once Upon a Time,” “Revenge,” “Scandal” and “Parenthood.” And starting Sunday, Netflix will start streaming the first season of “The Blacklist,” the shadowy espionage thriller with James Spader. Remember Robin Williams by watching “Good Morning, Vietnam” (1987), a mix of comedy and drama in which Williams draws on his mad improvisational skills to play a maverick deejay for the American troops fighting in Vietnam. You can see for yourself if the Academy got it wrong. ![]() Robert Redford gave one of the great performances of 2013 in “All is Lost.” Many critics thought it was worthy of an Oscar nomination. It’s inspired by a true story, believe it or not.Īvailable same day as theaters: the romantic comedy “The Longest Week” with Jason Bateman and Olivia Wilde, and the indie music drama “God Help the Girl,” the debut film from Stuart Murdoch of the band Belle & Sebastian.Īlso new: “Moms’ Night Out,” a PG family comedy with Patricia Heaton, and the documentary “For No Good Reason” on artist Ralph Steadman. You won’t recognize Michael Fassbender in the oddball comedy “Frank” because he wears a giant papier-mâché mask throughout the entire film. ![]() This is no Hollywood-style thriller but a low-key drama that explores the human equation in political action. and Peter Sarsgaard (Garden State) as three radical environmentalists that plan to execute a thrilling protest that will ultimately change all of their lives. Here’s a new film that hits close to home: “Night Moves” follows a trio of passionate eco-terrorists (Jesse Eisenberg, Dakota Fanning and Peter Sarsgaard) who blow up a dam on a southern Oregon river to make a “statement” and then unravel with guilt after a camper is killed as a result. What’s new to watch this week on pay-per-view and streaming services: Pay-per-view ![]() However, chemotherapy presents the disadvantages of poor efficacy, side effects, high recurrence, and low survival rate, which underlines the necessity of developing novel therapeutic strategies. Cisplatin (CDDP) is given intravenously as a short-term infusion of normal salinity for the treatment of solid and hematological malignancies, and its cytotoxic action is induced by interference with DNA replication, causing the death of cancerous cells. In the treatment of TNBC, two platinum-based drugs are currently used: cisplatin and carboplatin, which are administrated by intravenous injection. Chemotherapy remains the main systemic treatment option in TNBC, along with anthracyclines, taxanes, and platinum-based chemotherapeutics. The negative expression of ER, PR, and HER2 receptors renders it impossibile to use endocrine and targeted anti-HER2 therapies in the treatment of TNBC and reduces significantly the range of therapeutic possibilities. The TNBC is characterized by hyper-activation of the PI3K/Akt/mTOR pathway, which is correlated with the loss or inactivation of PTEN, PI3K mutation or amplification, and Akt and/or mTOR mutation. An important tumor suppressor of this pathway is represented by the phosphatase and tensin homolog (PTEN) which induces the dephosphorylation of PIP3 to PIP2, interrupting further signaling and resulting in cell growth inhibition. Moreover, the PI3K/Akt/mTOR pathway is negatively regulated by phosphatases. This protein causes the activation of the mTORC1 complex and induces protein synthesis, cell growth, proliferation, and survival. The most relevant downstream effector of PI3K is the serine/threonine kinase Akt, also known as protein kinase B. Furthermore, PIP3 can activate a variety of signaling proteins through the interaction between this phosphoinositide and their PH (pleckstrin homology) domain. Once activated, PI3K catalyzes the phosphorylation of phosphatidylinositol 4,5-bisphosphate (PIP2) to phosphatidylinositol 3,4,5-trisphosphate (PIP3). In normal conditions, the PI3K/Akt/mTOR pathway is activated by the binding of various stimuli (growth factors, hormones, cytokines) to receptor tyrosine kinases or G protein-coupled receptors which determine the recruitment of PI3K protein to the cellular membrane. One signaling pathway frequently dysregulated in TNBC and associated with uncontrolled cell proliferation, metabolism, and survival, which leads to the development and progression of cancer, is PI3K/Akt/mTOR. Moreover, TNBC tumors present high invasivity, increased expression of proliferation markers, high growth rate, and can rapidly metastasize to the brain, lungs, and liver. ![]() TNBC accounts for approximately 15–20% of total BC cases worldwide, is the most aggressive and heterogeneous subtype of BC, and, compared with other molecular subtypes of BC, it is associated with a poor prognosis, aggressive clinical behavior, low survival rates after recurrence, and early metastasis. Triple-negative breast cancer (TNBC) represents a special molecular subtype of breast cancer (BC) defined by the lack of three molecular biomarkers: estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2). Moreover, the nanoconjugates induced the downregulation of PI3K/Akt signaling, as revealed by the decreased expression of PI3K and p-Akt in parallel with PTEN activation, the promotion of Akt protein degradation, and inhibition of tumor cell migration. ![]() In vitro biological tests revealed that SWCNT-COOH-CDDP had a high cytotoxic effect, as shown by a time-dependent decrease in cell viability and the presence of a significant number of dead cells in MDA-MB-231 cultures at higher doses. MDA-MB-231 cells were exposed to various doses (0.01–2 µg/mL SWCNT-COOH and 0.00632–1.26 µg/mL CDDP) of SWCNT-COOH-CDDP and free components for 24 and 48 h. Hence, the main purpose of this study was to design a nanoconjugate based on single-walled carbon nanotubes functionalized with carboxyl groups (SWCNT-COOH) and cisplatin (CDDP) and to explore the potential of inhibiting the PI3K/Akt signaling pathway. Nowadays, the development of nanoparticle–drug conjugates attracts a great deal of attention due to the advantages they provide in cancer treatment. With considerable roles in tumor growth and proliferation, this pathway is studied as one of the main targets in controlling the therapies’ efficiency. PI3K/Akt signaling is one of the most frequently dysregulated pathways in cancer, including triple-negative breast cancer. ![]()
A reputable landscape contractor will carry liability and worker's compensation insurance coverage. ACLP contractors are experienced professionals who have passed extensive examinations covering all aspects of landscaping. Check to see if your contractor holds an AZ Certified Landscape Professional (ACLP) designation.Membership demonstrates a willingness to stay up to date on the latest techniques, newest trends and designs, and ever changing industry rules and regulations. Before hiring a landscape contractor, check for membership in ALCA, the only professional organization for landscape contractors in Arizona.A beautifully landscape project is a visible investment that leads to a substantial return. ALCA provides specialized training for its members so they utilize proper installation methods and best maintenance practices for their customers. When you contract with an ALCA member you are contracting with a landscape expert.The employee may be required to perform other related duties as requested to meet the ongoing needs of the organization. Note: This job description is not intended to be all-inclusive. i - Ability to work outdoors in various weather conditions - Physical stamina to perform manual labor and lift heavy objects if necessary - Attention to detail and ability to follow instructions QUALIFIED & Truly Interested Candidates: Please send your resume info via this In Deed ad and to E xpedite your chances of landing this great job, CALL - (602) 230-1220. Due to the Safety Sensitivity of this Position, we do conduct p re-employment and random drug testing which includes Marijuana and do a criminal background check as no Theft related felonies accepted.Hard work and dedication are rewarded with 2 raises in your first 7 months Possible as well as another as well as a possible 3rd raise 6 months after that. Individuals with prior Landscaping, Construction, Building Maintenance, Farm or Ranch Hands, Handyman Service or other general Maintenance and Repairs work history are also usually a good fit for this Jobas well as people who work on Cars, Motorcycles, ATV’s or landscape equipment at home. Prior Mechanical repair experience is a big plus & can result in a higher starting wage than those that do not, but again note it is not required. Familiarity with hand tools and power tools used in landscaping & Construction.Įquipment Service Techs also clean and do minor Maintenance on Equipment to get it ready to rent again which we are willing to train you on as long as you have enough Mechanical Aptitude to be able to learn things fairly quickly. You will also inspect it upon return for any damage and/or missing items. Job Description for Rental Yard Associates/Equipment Service Techs: With your excellent Customer Service skills You will help customers in person who come to our store/yard to pick-up or return rental equipment by loading, unloading as well as provide instruction on how to use the equipment including starting and stopping it. We can offer workers 3 days off each week (Work Four - 10 hour day shifts). NOTE: Rental Yardman have to work most all Saturdays (our Busiest Day) but you do get Sunday and at least one other day off and Note that Often…. Positions available Valley Wide - Central & North Phoenix, Avondale & Gilbert. Wanted: People who are good working with their hands, using Tools & Operating Equipment to assist the Customers of our client, a Locally Owned, Family Operated Equipment Rental Company founded in 1960. > lives in the States for additional confirmation. > and to a former FSN employee of VOA's Nairobi monitoring office who now > I have emails out to a BBC colleague at the monitoring office near Nairobi The recording lasts 30 seconds and during its first half there is strong. > language as Swahili though he could only pick out a few words. Figure 1 shows a 30 second recording made by Mauno Ritola 12.29 on 5th May, 2009. The Kenyan ham has come back and verified the > the language might be Swahili and offered to ask a ham friend in Kenya if > colleagues, Mauno Ritola and Vlad Titarev, for some help. I could not ID the language so asked a couple of experienced DX Radio Pakistan launched a Digital Medium Wave Transmitter project in Rawat on July 30th on the frequency 700 kHz. WRTH Publications Limited, 2014 - Radio broadcasting - 672 pages. > came across a weak voice under France on 1377 kHz just after 2100utc on Sean Gilbert, Mauno Ritola, Bernd Trutenau, John Nelson (Editor), George Jacobs (Editor). > While going through wav files from a recent DXpedition near Lubec, Maine I On ainakin tnn ness ihan schedulen mukaisesti, vaihtoi juuri 1930 espanjasta serbiksi. Us to hear Ukraine and China, also a low power Brit. ![]() There have been a few occasions when we found France off the air allowing What we discovered was that there appeared to be very few It's been heard in Newfoundland, though I recall that it came during anĪurora that completely wiped put all of Europe except for weak signalsįrom Spain. ![]() Irene) Koskinen Eero (Eric) Hellin Piispanen Mauno (Magnus) Ainikki. The main beam should naturally be towards Tibet to 205. Delivered-to: Delivered-to: Dkim-signature: v=1 a=rsa-sha256 c=relaxed/relaxed d= s=20120113 h=mime-version:in-reply-to:references:date:message-id:subject:from:to :content-type bh=exVm7VkbIC9GTsBrOdaidoRm6AsnP10Bo/kk0SvwM3o= b=i/aKRVycSrM5LAq3RYjjtJlrc2YhYo圆po2IN1iHlLJXPhXdYTzNirwjqcwSmtGClj lLHZG5TCxb7v3oEXJ8AuIIe9mfFbF8dlwZRCf9Ntgsg9S6kObg/FrxfoJmMRl2XBQD9B J3ueGpaY+Z3XvYdafUS4VtjcCgXzkjhQDJp0Y0f/2eOl1zqohfV/M0I8n483NrgPy2SmēUKZcTHBn7CE1vGIML4tO/2yq3bycEBBtYldsFZc/AustM5IxF+Ea7Ics/QklkI4bcYz lVVunPTo/vh94P5oC+qPHi5MP+eo5u9qgEUsT88dPv9gcNFDbygs4w+ER+lTSLyzHR7x RFFA= Yrj (George) Helmi Lallukka Vin Aili Ritola Armas Kyllikki Aitamurto Aarne. Mauno Ritola Tue, 12:36:28 -0800 I think I should have said 'maybe' instead of 'most probably' as we don't know the exact pattern of the system. ![]() To do this, see Create or delete a shortcut. You can check for corruption in shortcuts by recreating the shortcut. You can also receive this error if the shortcut or other file type has become corrupt. Method 4: Recreate the shortcut to check for corruption Browse to the location of the file and make sure the file is in that location. You can also receive this error if the file has been moved or deleted. ![]() Method 3: Make sure that the file has not been moved or deleted (The screen shot for this step is listed below). ![]() Check the path of the file that Windows cannot access and make sure that the location is accessible. You might get this error if the shortcut or installation is attempting to access a location that is not currently available such as a networked or a removable drive. (The screen shot for this step is listed below).įor more information on permissions, see What are permissions? Method 2: Check the file location Select Edit, and then select to check the check boxes for the permissions that you need, and then select OK. Under Group or User names, click your name to see the permissions you have. Right-click the file or folder, and then select Properties. To check the permission of the file or folder, follow these steps: Permissions are rules associated with files that determine if you can access the file and what you can do with it. Note Make sure you are an Administrator or you are part of the Domain Admins group if you are in a domain. Method 1: Check the permission of the file or folder To resolve this issue, follow the steps in the methods below starting with method 1, if that method does not resolve the issue continue to the next method. You may not have the appropriate permission to access the item Resolution Error: Windows cannot access the specified device, path, or file. ![]()
Their spiky debut single "Darts of Pleasure" arrived that September and reached number 44 on the U.K. Soon after, the band decamped to Malmö, Sweden to work with producer Tore Johansson at Gula Studios. The band needed a new rehearsal space once their illicit art parties were discovered by the police, and they found one in a Victorian courthouse and jail.īy mid-2002, Franz Ferdinand had recorded an EP's worth of material that they intended to release themselves, but word of mouth about the band spread and they signed to Domino in May 2003. Taking their name from the Austro-Hungarian Archduke whose murder sparked World War I (and hoping they'd have a similarly world-changing effect on music), Franz Ferdinand rehearsed at the Chateau and held rave-like events incorporating music and art ( Hardy graduated from the Glasgow School of Art, and Thomson also posed as a life model there). Eventually, McCarthy and Thomson switched instruments and the band switched practice spaces, moving to an abandoned warehouse that they named the Chateau. The trio had rehearsed at McCarthy's house for a while when they started playing with Thomson, who felt like playing guitar instead of drums. In late 2001, and bassist Bob Hardy began working on music together when they met Nick McCarthy, a classically trained pianist and double bass player who originally played drums for the group despite no prior experience as a drummer. ![]() Prior to forming Franz Ferdinand, singer/guitarist Alex Kapranos played in bands such as the Karelia and Yummy Fur (the latter of which also featured drummer Paul Thomson). The group continued to embellish on their signature sound in the 2020s, dabbling in electro pop and vintage glam influences on the new songs included on 2022's best-of Hits to the Head. ![]() On 2005's You Could Have It So Much Better, they added more detail and nuance to their style, then expanded on the danceable side of their music on albums ranging from the dub explorations of 2009's Tonight to the sleek disco leanings of 2018's Always Ascending. From the beginning, the group had a flair for translating arty and unexpected concepts and references into widely appealing music and visuals, whether it was the Russian Constructivism-inspired artwork that graced their early releases or the Howlin' Wolf homage in the guitar solos of 2004's smash single "Take Me Out." After laying the groundwork for their sound with that year's Mercury Prize-winning, platinum-selling, Grammy-nominated debut album Franz Ferdinand, the band soon branched out. While Franz Ferdinand had a kinship with those acts, their lineage also included the arch, angular post-punk of bands such as Wire and the witty, funky jangle of fellow Glaswegians Orange Juice. The Glasgow-based group arrived in the wake of the early-2000s rock revival, with bands such as the Strokes and the Libertines reminding listeners just how refreshing - and evergreen - hook-driven guitar music could be. ![]() With their sharply stylish mix of rock and dance music, Franz Ferdinand brought a wry sophistication to indie rock while becoming one of the U.K.'s most popular bands in the early 21st century. |
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